Reaction Details Report a problem with these data
Target
Serine/threonine-protein phosphatase
Ligand
BDBM64797
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
9927±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64797
Synonyms:
1,8-bis(azanyl)-6-propoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-6-propoxy-3-(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-6-propoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile | 1,8-diamino-6-propoxy-3-pyrrolidino-2,7-naphthyridine-4-carbonitrile | MLS000541660 | SMR000472233 | cid_11958363
Type:
Small organic molecule
Emp. Form.:
C16H20N6O
Mol. Mass.:
312.3696
SMILES:
CCCOc1cc2c(C#N)c(nc(N)c2c(N)n1)N1CCCC1
Structure:
Search PDB for entries with ligand similarity: