Reaction Details Report a problem with these data
Target
NADPH oxidase 1
Ligand
BDBM65849
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1)
IC50
>20000±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1) PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM65849
Synonyms:
N-[4-[(4-chlorophenyl)carbamoylamino]phenyl]-N-methyl-acetamide | N-[4-[(4-chlorophenyl)carbamoylamino]phenyl]-N-methyl-ethanamide | N-[4-[(4-chlorophenyl)carbamoylamino]phenyl]-N-methylacetamide | N-[4-[[(4-chloroanilino)-oxomethyl]amino]phenyl]-N-methylacetamide | SR-01000416457 | SR-01000416457-3 | cid_721945
Type:
Small organic molecule
Emp. Form.:
C16H16ClN3O2
Mol. Mass.:
317.77
SMILES:
CN(C(C)=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1
Structure:
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