Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM66022
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
10980±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM66022
Synonyms:
KE-IK | MLS002153668 | SMR001231046 | cid_25163004
Type:
Small organic molecule
Emp. Form.:
C67H116N18O9
Mol. Mass.:
1317.7531
SMILES:
CC[C@H](C)Cc1cn(nn1)[C@@H](CCCCN)C(=O)NCCCCCCCCCCC(=O)N1CCN(CC1)c1nc(NCCOCCOCCOCC#C)nc(n1)N1CCN(CC1)C(=O)CCCCCCCCCCNC(=O)[C@@H](CCC(O)=O)n1cc(CCCCCN)nn1
Structure:
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