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Target
Vacuolar aminopeptidase 1
Ligand
BDBM66046
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
EC50
31710±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM66046
Synonyms:
(3,5-dichloro-2-pyridyl)-[(5-methyl-2-thienyl)methyleneamino]amine | 3,5-bis(chloranyl)-N-[(5-methylthiophen-2-yl)methylideneamino]pyridin-2-amine | 3,5-dichloro-N-[(5-methyl-2-thiophenyl)methylideneamino]-2-pyridinamine | 3,5-dichloro-N-[(5-methylthiophen-2-yl)methylideneamino]pyridin-2-amine | MLS000565753 | SMR000152929 | cid_3936928
Type:
Small organic molecule
Emp. Form.:
C11H9Cl2N3S
Mol. Mass.:
286.18
SMILES:
Cc1ccc(CN=Nc2ncc(Cl)cc2Cl)s1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: