Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66236
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66236
Synonyms:
(5E)-2,2-dimethyl-4,6-dioxo-5-[1-(1-pyrrolidinyl)propylidene]-1-cyclohexanecarboxylic acid methyl ester | (5E)-4,6-diketo-2,2-dimethyl-5-(1-pyrrolidinopropylidene)cyclohexanecarboxylic acid methyl ester | MLS000078909 | SMR000040467 | cid_659398 | methyl (5E)-2,2-dimethyl-4,6-bis(oxidanylidene)-5-(1-pyrrolidin-1-ylpropylidene)cyclohexane-1-carboxylate | methyl (5E)-2,2-dimethyl-4,6-dioxo-5-(1-pyrrolidin-1-ylpropylidene)cyclohexane-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H25NO4
Mol. Mass.:
307.3847
SMILES:
CCC(N1CCCC1)=C1C(=O)CC(C)(C)C(C(=O)OC)C1=O |w:8.21|
Structure:
Search PDB for entries with ligand similarity: