Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM31064
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM31064
Synonyms:
4-(2-furanyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine | 4-(2-furyl)-2-(methylsulfonyl)-6-(trifluoromethyl)pyrimidine | 4-(2-furyl)-2-mesyl-6-(trifluoromethyl)pyrimidine | 4-(furan-2-yl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine | MLS000044646 | SMR000022590 | cid_3237865
Type:
Small organic molecule
Emp. Form.:
C10H7F3N2O3S
Mol. Mass.:
292.234
SMILES:
CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: