Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM57053
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM57053
Synonyms:
MLS000068601 | N-(4-Bromo-phenyl)-2-(3-cyano-4-methyl-6-oxo-1,6-dihydro-pyridin-2-ylsulfanyl)-acetamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxidanylidene-1H-pyridin-2-yl)sulfanyl]ethanamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxo-1H-pyridin-2-yl)sulfanyl]acetamide | N-(4-bromophenyl)-2-[(3-cyano-4-methyl-6-oxo-1H-pyridin-2-yl)thio]acetamide | N-(4-bromophenyl)-2-[(3-cyano-6-keto-4-methyl-1H-pyridin-2-yl)thio]acetamide | SMR000122935 | cid_1069285
Type:
Small organic molecule
Emp. Form.:
C15H12BrN3O2S
Mol. Mass.:
378.244
SMILES:
Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Br)cc2)c1C#N
Structure:
Search PDB for entries with ligand similarity: