Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM66318
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66318
Synonyms:
1-naphthylmethyl-[4-[(1H-1,2,4-triazol-5-ylamino)methyl]phenyl]amine | MLS000527788 | N-[[4-(1-naphthalenylmethylamino)phenyl]methyl]-1H-1,2,4-triazol-5-amine | N-[[4-(naphthalen-1-ylmethylamino)phenyl]methyl]-1H-1,2,4-triazol-5-amine | SMR000120362 | cid_851519 | {4-[(Naphthalen-1-ylmethyl)-amino]-benzyl}-(2H-[1,2,4]triazol-3-yl)-amine
Type:
Small organic molecule
Emp. Form.:
C20H19N5
Mol. Mass.:
329.3984
SMILES:
C(Nc1nnc[nH]1)c1ccc(NCc2cccc3ccccc23)cc1
Structure:
Search PDB for entries with ligand similarity: