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Target
Bcl-2-like protein 11
Ligand
BDBM66443
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM66443
Synonyms:
1-(4-Chloro-benzoyl)-1-ethyl-2-oxo-1,7b-dihydro-cyclopropa[c]chromene-1a-carboxylic acid phenylamide | 1-(4-chlorobenzoyl)-1-ethyl-2-keto-N-phenyl-7bH-cyclopropa[c]chromene-1a-carboxamide | 1-(4-chlorobenzoyl)-1-ethyl-2-oxo-N-phenyl-7bH-cyclopropa[c]chromene-1a-carboxamide | 1-(4-chlorophenyl)carbonyl-1-ethyl-2-oxidanylidene-N-phenyl-7bH-cyclopropa[c]chromene-1a-carboxamide | 1-[(4-chlorophenyl)-oxomethyl]-1-ethyl-2-oxo-N-phenyl-7bH-cyclopropa[c][1]benzopyran-1a-carboxamide | MLS000580328 | SMR000220559 | cid_3327006
Type:
Small organic molecule
Emp. Form.:
C26H20ClNO4
Mol. Mass.:
445.894
SMILES:
CCC1(C2c3ccccc3OC(=O)C12C(=O)Nc1ccccc1)C(=O)c1ccc(Cl)cc1
Structure:
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