Reaction Details Report a problem with these data
Target
Serine/threonine-protein kinase 33
Ligand
BDBM51558
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
15970±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM51558
Synonyms:
5-bromanyl-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)furan-2-carboxamide | 5-bromo-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)-2-furamide | 5-bromo-N-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)furan-2-carboxamide | 5-bromo-N-[3-(2-imidazo[1,2-a]pyrimidinyl)phenyl]-2-furancarboxamide | MLS000045937 | SMR000028309 | cid_3241738
Type:
Small organic molecule
Emp. Form.:
C17H11BrN4O2
Mol. Mass.:
383.199
SMILES:
Brc1ccc(o1)C(=O)Nc1cccc(c1)-c1cn2cccnc2n1
Structure:
Search PDB for entries with ligand similarity: