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Target
Serine/threonine-protein kinase 33
Ligand
BDBM67579
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
>120000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM67579
Synonyms:
2-[(4,6-di-1-piperidinyl-1,3,5-triazin-2-yl)thio]-1-phenylethanone | 2-[(4,6-dipiperidino-s-triazin-2-yl)thio]-1-phenyl-ethanone | 2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]thio]-1-phenylethanone | 2-[[4,6-di(piperidin-1-yl)-1,3,5-triazin-2-yl]sulfanyl]-1-phenyl-ethanone | 2-[[4,6-di(piperidin-1-yl)-1,3,5-triazin-2-yl]sulfanyl]-1-phenylethanone | MLS000051319 | SMR000079399 | cid_1263560
Type:
Small organic molecule
Emp. Form.:
C21H27N5OS
Mol. Mass.:
397.537
SMILES:
O=C(CSc1nc(nc(n1)N1CCCCC1)N1CCCCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: