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Target
Serine/threonine-protein kinase 33
Ligand
BDBM67585
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
2481±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM67585
Synonyms:
1-(6-acetohydroximoyl-9-propyl-carbazol-3-yl)ethanone oxime | 1-(6-{1-[(Z)-Hydroxyimino]-ethyl}-9-propyl-9H-carbazol-3-yl)-ethanone oxime | 1-[6-(1-hydroxyiminoethyl)-9-propyl-3-carbazolyl]ethanone oxime | MLS000554342 | N-[1-[6-(C-methyl-N-oxidanyl-carbonimidoyl)-9-propyl-carbazol-3-yl]ethylidene]hydroxylamine | N-[1-[6-(N-hydroxy-C-methylcarbonimidoyl)-9-propylcarbazol-3-yl]ethylidene]hydroxylamine | SMR000146659 | cid_916005
Type:
Small organic molecule
Emp. Form.:
C19H21N3O2
Mol. Mass.:
323.3889
SMILES:
CCCn1c2ccc(cc2c2cc(ccc12)C(C)N=O)C(C)N=O
Structure:
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