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Target
Serine/threonine-protein kinase 33
Ligand
BDBM33092
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
>120000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM33092
Synonyms:
4-N,4-N-diethyl-1-N-(4-morpholin-4-ylquinazolin-2-yl)benzene-1,4-diamine | MLS000564383 | N4,N4-diethyl-N1-(4-morpholin-4-ylquinazolin-2-yl)benzene-1,4-diamine | N4,N4-diethyl-N1-[4-(4-morpholinyl)-2-quinazolinyl]benzene-1,4-diamine | SMR000151933 | cid_2347431 | diethyl-[4-[(4-morpholinoquinazolin-2-yl)amino]phenyl]amine
Type:
Small organic molecule
Emp. Form.:
C22H27N5O
Mol. Mass.:
377.4827
SMILES:
CCN(CC)c1ccc(Nc2nc(N3CCOCC3)c3ccccc3n2)cc1
Structure:
Search PDB for entries with ligand similarity: