Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM43209
Substrate
n/a
Meas. Tech.
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
IC50
5550±n/a nM
Citation
 PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay (2010)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
DDIT3_MOUSE | Ddit3 | Chop | Chop10 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mouse
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM43209
Synonyms:
MLS000537345 | 1-(3-methoxyphenyl)-5-methylsulfonyltetrazole | 1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazole | 1-(3-methoxyphenyl)-5-methylsulfonyl-1,2,3,4-tetrazole | SMR000143783 | cid_2221997 | 5-mesyl-1-(3-methoxyphenyl)tetrazole
Type:
Small organic molecule
Emp. Form.:
C9H10N4O3S
Mol. Mass.:
254.05
SMILES:
COc1cccc(c1)-n1nnnc1S(C)(=O)=O
Structure:
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