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Target
ATP-dependent molecular chaperone HSP82
Ligand
BDBM57744
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
EC50
44970±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 PubChem Bioassay (2010)[AID] 
Target
Name:
ATP-dependent molecular chaperone HSP82
Synonyms:
heat shock protein 90
Type:
Enzyme Catalytic Domain
Mol. Mass.:
80784.12
Organism:
Candida albicans
Description:
gi_994798
Residue:
707
Sequence:
MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
  
Inhibitor
Name:
BDBM57744
Synonyms:
4-chloranyl-N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]benzamide | 4-chloro-N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]benzamide | 4-chloro-N-[5-(2-furyl)-1,3,4-oxadiazol-2-yl]benzamide | 4-chloro-N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]benzamide | MLS000683071 | SMR000323146 | cid_5223276
Type:
Small organic molecule
Emp. Form.:
C13H8ClN3O3
Mol. Mass.:
289.674
SMILES:
Clc1ccc(cc1)C(=O)Nc1nnc(o1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: