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Target
Heat shock factor protein 1
Ligand
BDBM50929
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
EC50
14180±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM50929
Synonyms:
(E)-1-(1-benzotriazolyl)-3-(4-propan-2-ylphenyl)-2-propen-1-one | (E)-1-(benzotriazol-1-yl)-3-(4-propan-2-ylphenyl)prop-2-en-1-one | (E)-1-(benzotriazol-1-yl)-3-p-cumenyl-prop-2-en-1-one | 1-[3-(4-isopropylphenyl)acryloyl]-1H-1,2,3-benzotriazole | MLS000543635 | SMR000163707 | cid_6016133
Type:
Small organic molecule
Emp. Form.:
C18H17N3O
Mol. Mass.:
291.3471
SMILES:
CC(C)c1ccc(\C=C\C(=O)n2nnc3ccccc23)cc1
Structure:
Search PDB for entries with ligand similarity: