Reaction Details Report a problem with these data
Target
Heat shock factor protein 1
Ligand
BDBM54829
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
EC50
3487±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM54829
Synonyms:
2-(7-Chloro-4-nitro-benzo[1,2,5]oxadiazol-5-ylamino)-phenol | 6-[(7-chloranyl-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[(7-chloro-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]-1-cyclohexa-2,4-dienone | 6-[(7-chloro-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[(7-chloro-4-nitro-1,3-dihydrobenzofurazan-5-yl)imino]cyclohexa-2,4-dien-1-one | MLS001210732 | SMR000516448 | cid_5719581
Type:
Small organic molecule
Emp. Form.:
C12H7ClN4O4
Mol. Mass.:
306.661
SMILES:
[O-]c1ccccc1Nc1cc(Cl)c2[nH+]onc2c1[N+]([O-])=O
Structure:
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