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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM69062
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM69062
Synonyms:
6-(5-chloranyl-2-methoxy-phenyl)-N2-cyclohexyl-1,3,5-triazine-2,4-diamine | 6-(5-chloro-2-methoxyphenyl)-2-N-cyclohexyl-1,3,5-triazine-2,4-diamine | 6-(5-chloro-2-methoxyphenyl)-N2-cyclohexyl-1,3,5-triazine-2,4-diamine | MLS000698409 | N-[4-amino-6-(5-chloro-2-methoxyphenyl)-1,3,5-triazin-2-yl]-N-cyclohexylamine | SMR000224919 | [4-amino-6-(5-chloro-2-methoxy-phenyl)-s-triazin-2-yl]-cyclohexyl-amine | cid_826987
Type:
Small organic molecule
Emp. Form.:
C16H20ClN5O
Mol. Mass.:
333.816
SMILES:
COc1ccc(Cl)cc1-c1nc(N)nc(NC2CCCCC2)n1
Structure:
Search PDB for entries with ligand similarity: