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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74508
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74508
Synonyms:
3-(2-chlorophenyl)-5-methyl-N-[1-[3-(2-methylpropanoylamino)phenyl]ethylideneamino]-1,2-oxazole-4-carboxamide | 3-(2-chlorophenyl)-5-methyl-N-[1-[3-[(2-methyl-1-oxopropyl)amino]phenyl]ethylideneamino]-4-isoxazolecarboxamide | 3-(2-chlorophenyl)-N-[1-[3-(isobutyrylamino)phenyl]ethylideneamino]-5-methyl-isoxazole-4-carboxamide | MLS000699659 | N-[3-(N-{[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl}ethanehydrazonoyl)phenyl]-2-methylpropanamide | SMR000227444 | cid_1223922
Type:
Small organic molecule
Emp. Form.:
C23H23ClN4O3
Mol. Mass.:
438.907
SMILES:
CC(C)C(=O)Nc1cccc(c1)C(C)=NNC(=O)c1c(C)onc1-c1ccccc1Cl |w:14.15|
Structure:
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