Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75352
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75352
Synonyms:
2-chloranyl-5-(5-pyridin-3-yl-1,2,3,4-tetrazol-2-yl)pyridine | 2-chloro-5-(5-pyridin-3-yltetrazol-2-yl)pyridine | 2-chloro-5-[5-(3-pyridinyl)-2-tetrazolyl]pyridine | 2-chloro-5-[5-(3-pyridyl)tetrazol-2-yl]pyridine | MLS-0067120.0001 | cid_16654621
Type:
Small organic molecule
Emp. Form.:
C11H7ClN6
Mol. Mass.:
258.666
SMILES:
Clc1ccc(cn1)-n1nnc(n1)-c1cccnc1
Structure:
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