Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM52365
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R)
EC50
4753±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R) PubChem Bioassay (2010)[AID] 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM52365
Synonyms:
2-(2-Hydroxy-ethyl)-6-piperidin-1-yl-benzo[de]isoquinoline-1,3-dione | 2-(2-hydroxyethyl)-6-(1-piperidinyl)benzo[de]isoquinoline-1,3-dione | 2-(2-hydroxyethyl)-6-piperidin-1-yl-benzo[de]isoquinoline-1,3-dione | 2-(2-hydroxyethyl)-6-piperidin-1-ylbenzo[de]isoquinoline-1,3-dione | 2-(2-hydroxyethyl)-6-piperidino-benzo[de]isoquinoline-1,3-quinone | MLS000563420 | SMR000176434 | cid_2871994
Type:
Small organic molecule
Emp. Form.:
C19H20N2O3
Mol. Mass.:
324.3737
SMILES:
OCCN1C(=O)c2cccc3c(ccc(C1=O)c23)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: