Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM76046
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
IC50
31500±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM76046
Synonyms:
1-cyclopentyl-N-(2-furanylmethyl)-2-imino-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 1-cyclopentyl-N-(2-furfuryl)-2-imino-5-keto-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 1-cyclopentyl-N-(furan-2-ylmethyl)-2-imino-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-azanylidene-1-cyclopentyl-N-(furan-2-ylmethyl)-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS-0332635.0001 | cid_1077536
Type:
Small organic molecule
Emp. Form.:
C22H21N5O3
Mol. Mass.:
403.4338
SMILES:
N=c1c(cc2c(nc3ccccn3c2=O)n1C1CCCC1)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: