Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM75384
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM75384
Synonyms:
2-[4-(2-furanylmethyl)-5-[(2,3,4-trifluorophenyl)methylthio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(2-furfuryl)-5-[(2,3,4-trifluorobenzyl)thio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(furan-2-ylmethyl)-5-[(2,3,4-trifluorophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine | 2-[4-(furan-2-ylmethyl)-5-[[2,3,4-tris(fluoranyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine | KSC-5-287B12 | KUC104187N | cid_44620919
Type:
Small organic molecule
Emp. Form.:
C19H13F3N4OS
Mol. Mass.:
402.393
SMILES:
Fc1ccc(CSc2nnc(-c3ccccn3)n2Cc2ccco2)c(F)c1F
Structure:
Search PDB for entries with ligand similarity: