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Target
Kappa-type opioid receptor
Ligand
BDBM75379
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay-Set 3
EC50
28700±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay-Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM75379
Synonyms:
2-[4-(2-furanylmethyl)-5-[(2-methylphenyl)methylthio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(2-furfuryl)-5-[(2-methylbenzyl)thio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(furan-2-ylmethyl)-5-[(2-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine | KSC-5-287A7 | KUC104182N | cid_16447357
Type:
Small organic molecule
Emp. Form.:
C20H18N4OS
Mol. Mass.:
362.448
SMILES:
Cc1ccccc1CSc1nnc(-c2ccccn2)n1Cc1ccco1
Structure:
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