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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM50629
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.
EC50
91300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM50629
Synonyms:
(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-3-(4-hydroxyphenyl)-2-sulfanylidene-4-thiazolidinone | (5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-3-(4-hydroxyphenyl)-2-thioxo-thiazolidin-4-one | (5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-3-(4-hydroxyphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one | 5-[(E)-3-Furan-2-yl-prop-2-en-(Z)-ylidene]-3-(4-hydroxy-phenyl)-2-thioxo-thiazolidin-4-one | MLS000778636 | SMR000415430 | cid_6241261
Type:
Small organic molecule
Emp. Form.:
C16H11NO3S2
Mol. Mass.:
329.393
SMILES:
Oc1ccc(cc1)N1C(=S)S\C(=C/C=C/c2ccco2)C1=O
Structure:
Search PDB for entries with ligand similarity: