Reaction Details Report a problem with these data
Target
Protein RecA
Ligand
BDBM31061
Substrate
n/a
Meas. Tech.
Intein inhibitors as potential Tuberculosis drugs
IC50
5980±n/a nM
Citation
 PubChem, PC Intein inhibitors as potential Tuberculosis drugs PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM31061
Synonyms:
4-[1-(4-chlorophenyl)tetrazol-5-yl]sulfanylthieno[2,3-d]pyrimidine | 4-[[1-(4-chlorophenyl)-1,2,3,4-tetrazol-5-yl]sulfanyl]thieno[2,3-d]pyrimidine | 4-[[1-(4-chlorophenyl)-5-tetrazolyl]thio]thieno[2,3-d]pyrimidine | 4-[[1-(4-chlorophenyl)tetrazol-5-yl]thio]thieno[2,3-d]pyrimidine | MLS000058692 | SMR000066808 | cid_2112599
Type:
Small organic molecule
Emp. Form.:
C13H7ClN6S2
Mol. Mass.:
346.818
SMILES:
Clc1ccc(cc1)-n1nnnc1Sc1ncnc2sccc12
Structure:
Search PDB for entries with ligand similarity: