Reaction Details Report a problem with these data
Target
Protein RecA
Ligand
BDBM58117
Substrate
n/a
Meas. Tech.
Intein inhibitors as potential Tuberculosis drugs
IC50
>100000±n/a nM
Citation
 PubChem, PC Intein inhibitors as potential Tuberculosis drugs PubChem Bioassay (2010)[AID] 
Target
Name:
Protein RecA
Synonyms:
DNA recombination protein RecA | RECA_MYCTU | recA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
85386.52
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15609874
Residue:
790
Sequence:
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
  
Inhibitor
Name:
BDBM58117
Synonyms:
1-(2-Hydroxy-ethylamino)-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid (2-diethylamino-ethyl)-amide | MLS000770002 | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-bis(oxidanylidene)anthracene-2-carboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-diketo-anthracene-2-carboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-dioxo-2-anthracenecarboxamide | N-[2-(diethylamino)ethyl]-1-(2-hydroxyethylamino)-9,10-dioxoanthracene-2-carboxamide | SMR000434735 | cid_3737083
Type:
Small organic molecule
Emp. Form.:
C23H27N3O4
Mol. Mass.:
409.4782
SMILES:
CCN(CC)CCNC(=O)c1ccc2C(=O)c3ccccc3C(=O)c2c1NCCO
Structure:
Search PDB for entries with ligand similarity: