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Target
Caspase-3
Ligand
BDBM77495
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3
EC50
>85251±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-3
Synonyms:
Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein
Type:
Hydrolase; heterotetramer of two heterodimers
Mol. Mass.:
31607.55
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
277
Sequence:
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
  
Inhibitor
Name:
BDBM77495
Synonyms:
4-(m-anisoylamino)-2,3-dihydrothiophene-5-carboxylic acid methyl ester | 4-[[(3-methoxyphenyl)-oxomethyl]amino]-2,3-dihydrothiophene-5-carboxylic acid methyl ester | MLS000087766 | SMR000023986 | cid_3241864 | methyl 3-[(3-methoxybenzoyl)amino]-4,5-dihydrothiophene-2-carboxylate | methyl 4-[(3-methoxybenzoyl)amino]-2,3-dihydrothiophene-5-carboxylate | methyl 4-[(3-methoxyphenyl)carbonylamino]-2,3-dihydrothiophene-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H15NO4S
Mol. Mass.:
293.338
SMILES:
COC(=O)C1=C(CCS1)NC(=O)c1cccc(OC)c1 |t:4|
Structure:
Search PDB for entries with ligand similarity: