Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM48913
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
60300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM48913
Synonyms:
MLS000068928 | N-(5-Methyl-isoxazol-3-yl)-2-phenoxy-benzamide | N-(5-methyl-1,2-oxazol-3-yl)-2-phenoxy-benzamide | N-(5-methyl-1,2-oxazol-3-yl)-2-phenoxybenzamide | N-(5-methyl-3-isoxazolyl)-2-phenoxybenzamide | N-(5-methylisoxazol-3-yl)-2-phenoxy-benzamide | SMR000011803 | cid_652253
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3
Mol. Mass.:
294.3047
SMILES:
Cc1cc(NC(=O)c2ccccc2Oc2ccccc2)no1
Structure:
Search PDB for entries with ligand similarity: