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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78555
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
982±69 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78555
Synonyms:
6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperidin-1-ylsulfonyl)phenyl]hexanamide | 6-(1,3-dioxo-2-isoindolyl)-N-[4-(1-piperidinylsulfonyl)phenyl]hexanamide | 6-(1,3-dioxoisoindol-2-yl)-N-(4-piperidin-1-ylsulfonylphenyl)hexanamide | 6-[1,3-bis(oxidanylidene)isoindol-2-yl]-N-(4-piperidin-1-ylsulfonylphenyl)hexanamide | 6-phthalimido-N-(4-piperidinosulfonylphenyl)hexanamide | MLS000085228 | SMR000019768 | cid_3243667
Type:
Small organic molecule
Emp. Form.:
C25H29N3O5S
Mol. Mass.:
483.58
SMILES:
O=C(CCCCCN1C(=O)c2ccccc2C1=O)Nc1ccc(cc1)S(=O)(=O)N1CCCCC1
Structure:
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