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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM61015
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM61015
Synonyms:
3-(4-fluorophenyl)-7,8-dimethoxy-5-(phenylmethyl)pyrazolo[4,3-c]quinoline | 5-benzyl-3-(4-fluorophenyl)-7,8-dimethoxy-pyrazolo[4,3-c]quinoline | 5-benzyl-3-(4-fluorophenyl)-7,8-dimethoxypyrazolo[4,3-c]quinoline | MLS000530082 | SMR000127107 | cid_2136878
Type:
Small organic molecule
Emp. Form.:
C25H20FN3O2
Mol. Mass.:
413.4436
SMILES:
COc1cc2n(Cc3ccccc3)cc3c(nnc3c2cc1OC)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: