Reaction Details Report a problem with these data
Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78962
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78962
Synonyms:
2-(6-chloranyl-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride | 2-(6-chloro-4-phenyl-2-quinazolinyl)guanidine;hydrochloride | 2-(6-chloro-4-phenyl-quinazolin-2-yl)guanidine;hydrochloride | 2-(6-chloro-4-phenylquinazolin-2-yl)guanidine;hydrochloride | MLS001206456 | N-(6-Chloro-4-phenyl-quinazolin-2-yl)-guanidine | SMR000518356 | cid_24746808
Type:
Small organic molecule
Emp. Form.:
C15H12ClN5
Mol. Mass.:
297.742
SMILES:
[#7]\[#6](-[#7])=[#7]\c1nc(-c2ccccc2)c2cc(Cl)ccc2n1
Structure:
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