Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM41826
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
7110±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM41826
Synonyms:
2-[[(4E)-1-keto-4-(2-thienylsulfonylimino)-2-naphthyl]amino]benzoic acid methyl ester | 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonylimino-2-naphthalenyl]amino]benzoic acid methyl ester | MLS000521465 | SMR000131873 | cid_9550941 | methyl 2-[[(4E)-1-oxidanylidene-4-thiophen-2-ylsulfonylimino-naphthalen-2-yl]amino]benzoate | methyl 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonyliminonaphthalen-2-yl]amino]benzoate
Type:
Small organic molecule
Emp. Form.:
C22H16N2O5S2
Mol. Mass.:
452.503
SMILES:
COC(=O)c1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O |w:14.15,t:12|
Structure:
Search PDB for entries with ligand similarity: