Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM63381
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
10000±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM63381
Synonyms:
(5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-[4-(dimethylamino)benzylidene]thiazolidine-2,4-quinone | (5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-[[4-(dimethylamino)phenyl]methylidene]-1,3-thiazolidine-2,4-dione | (5Z)-3-[2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl]-5-[[4-(dimethylamino)phenyl]methylidene]thiazolidine-2,4-dione | (5Z)-3-[2-(5-azanyl-1,3,4-thiadiazol-2-yl)ethyl]-5-[[4-(dimethylamino)phenyl]methylidene]-1,3-thiazolidine-2,4-dione | MLS000402370 | SMR000263698 | cid_1539603
Type:
Small organic molecule
Emp. Form.:
C16H17N5O2S2
Mol. Mass.:
375.468
SMILES:
CN(C)c1ccc(\C=C2/SC(=O)N(CCc3nnc(N)s3)C2=O)cc1
Structure:
Search PDB for entries with ligand similarity: