Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM65733
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
4630±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM65733
Synonyms:
3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione | 7-benzyl-3-methyl-8-nitro-xanthine | 7-benzyl-3-methyl-8-nitropurine-2,6-dione | MLS-0298349.0001 | cid_909915
Type:
Small organic molecule
Emp. Form.:
C13H11N5O4
Mol. Mass.:
301.2575
SMILES:
Cn1c2nc(n(Cc3ccccc3)c2c(=O)[nH]c1=O)[N+]([O-])=O
Structure:
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