Reaction Details Report a problem with these data
Target
Neurotensin receptor type 1
Ligand
BDBM79549
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
13300±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79549
Synonyms:
MLS000666198 | N-[3-[(E)-3-(4-bromophenyl)-1-oxoprop-2-enyl]phenyl]acetamide | N-[3-[(E)-3-(4-bromophenyl)acryloyl]phenyl]acetamide | N-[3-[(E)-3-(4-bromophenyl)prop-2-enoyl]phenyl]acetamide | N-[3-[(E)-3-(4-bromophenyl)prop-2-enoyl]phenyl]ethanamide | N-{3-[3-(4-bromophenyl)acryloyl]phenyl}acetamide | SMR000271513 | cid_5735866
Type:
Small organic molecule
Emp. Form.:
C17H14BrNO2
Mol. Mass.:
344.203
SMILES:
CC(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(Br)cc1
Structure:
Search PDB for entries with ligand similarity: