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Target
Tropomyosin alpha-1 chain
Ligand
BDBM69027
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50
>71500±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM69027
Synonyms:
1-[[3-(3,4-dimethoxyphenyl)-1-phenyl-pyrazol-4-yl]methylideneamino]thiourea | MLS000375184 | SMR000254437 | [[3-(3,4-dimethoxyphenyl)-1-phenyl-4-pyrazolyl]methylideneamino]thiourea | [[3-(3,4-dimethoxyphenyl)-1-phenyl-pyrazol-4-yl]methyleneamino]thiourea | [[3-(3,4-dimethoxyphenyl)-1-phenylpyrazol-4-yl]methylideneamino]thiourea | cid_2363859
Type:
Small organic molecule
Emp. Form.:
C19H19N5O2S
Mol. Mass.:
381.451
SMILES:
COc1ccc(cc1OC)-c1nn(cc1C=NNC(N)=S)-c1ccccc1 |w:16.18|
Structure:
Search PDB for entries with ligand similarity: