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Target
DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80387
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2350±174 nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
  
Inhibitor
Name:
BDBM80387
Synonyms:
(3-methyl-1,3-thiazinan-2-ylidene)-p-phenetyl-amine;hydroiodide | (4-Ethoxy-phenyl)-(3-methyl-[1,3]thiazinan-2-ylidene)-amine | MLS000122383 | N-(4-ethoxyphenyl)-3-methyl-1,3-thiazinan-2-imine;hydroiodide | SMR000119742 | cid_9549417
Type:
Small organic molecule
Emp. Form.:
C13H18N2OS
Mol. Mass.:
250.36
SMILES:
CCOc1ccc(cc1)\N=C1\SCCCN1C
Structure:
Search PDB for entries with ligand similarity: