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Target
DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80401
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2010±240 nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
  
Inhibitor
Name:
BDBM80401
Synonyms:
2-[(4-chlorobenzyl)-(2-pyridyl)amino]ethyl-trimethyl-ammonium;iodide | 2-[(4-chlorophenyl)methyl-(2-pyridinyl)amino]ethyl-trimethylammonium;iodide | 2-[(4-chlorophenyl)methyl-pyridin-2-yl-amino]ethyl-trimethyl-azanium;iodide | 2-[(4-chlorophenyl)methyl-pyridin-2-ylamino]ethyl-trimethylazanium;iodide | MLS000556881 | SMR000147998 | cid_9551614 | {2-[(4-Chloro-benzyl)-pyridin-2-yl-amino]-ethyl}-trimethyl-ammonium
Type:
Small organic molecule
Emp. Form.:
C17H23ClN3
Mol. Mass.:
304.837
SMILES:
C[N+](C)(C)CCN(Cc1ccc(Cl)cc1)c1ccccn1
Structure:
Search PDB for entries with ligand similarity: