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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80418
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2190±106 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80418
Synonyms:
1-butyl-3-(diphenylmethylene)-1-azoniabicyclo[2.2.2]octane;bromide | 1-butyl-3-(diphenylmethylidene)-1-azoniabicyclo[2.2.2]octane;bromide | 3-benzhydrylidene-1-butyl-1-azoniabicyclo[2.2.2]octane;bromide | 3-benzhydrylidene-1-butyl-quinuclidin-1-ium;bromide | MLS000591151 | SMR000217939 | cid_12004471
Type:
Small organic molecule
Emp. Form.:
C24H30BrN
Mol. Mass.:
412.406
SMILES:
n/a
Structure:
