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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80498
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
2090±302 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80498
Synonyms:
(1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-(hydroxymethyl)-2-phenyl-butanoate;iodide | (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-(hydroxymethyl)-2-phenylbutanoate;iodide | 2-(hydroxymethyl)-2-phenylbutanoic acid (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) ester;iodide | 2-methylol-2-phenyl-butyric acid (1-methylquinuclidin-1-ium-3-yl) ester;iodide | MLS000693647 | SMR000285439 | cid_16192995
Type:
Small organic molecule
Emp. Form.:
C19H28INO3
Mol. Mass.:
445.335
SMILES:
n/a
Structure:
