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Target
C-C chemokine receptor type 6
Ligand
BDBM79982
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
42600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM79982
Synonyms:
3-propoxy-N-[[3-(trifluoromethyl)phenyl]carbamothioyl]benzamide | 3-propoxy-N-[[3-(trifluoromethyl)phenyl]thiocarbamoyl]benzamide | 3-propoxy-N-[sulfanylidene-[3-(trifluoromethyl)anilino]methyl]benzamide | MLS000545074 | N-(3-propoxybenzoyl)-N'-[3-(trifluoromethyl)phenyl]thiourea | SMR000160802 | cid_1716237
Type:
Small organic molecule
Emp. Form.:
C18H17F3N2O2S
Mol. Mass.:
382.4
SMILES:
CCCOc1cccc(c1)C(=O)NC(=S)Nc1cccc(c1)C(F)(F)F
Structure:
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