Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM70626
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
65700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM70626
Synonyms:
4-(1-benzotriazolyl)-3,5-dinitrobenzonitrile | 4-(1H-1,2,3-benzotriazol-1-yl)-3,5-bisnitrobenzonitrile | 4-(benzotriazol-1-yl)-3,5-dinitro-benzenecarbonitrile | 4-(benzotriazol-1-yl)-3,5-dinitro-benzonitrile | 4-(benzotriazol-1-yl)-3,5-dinitrobenzonitrile | MLS000545635 | SMR000163394 | cid_1827281
Type:
Small organic molecule
Emp. Form.:
C13H6N6O4
Mol. Mass.:
310.2245
SMILES:
[O-][N+](=O)c1cc(cc(c1-n1nnc2ccccc12)[N+]([O-])=O)C#N |(11.73,-1.32,;10.22,-1.63,;9.74,-3.1,;9.19,-.49,;9.67,.98,;8.64,2.12,;7.13,1.8,;6.65,.34,;7.68,-.81,;7.2,-2.27,;8.1,-3.51,;7.2,-4.75,;5.75,-4.28,;4.41,-5.05,;3.08,-4.28,;3.08,-2.74,;4.41,-1.97,;5.75,-2.74,;5.19,.82,;4.87,2.33,;4.04,-.21,;9.12,3.59,;9.6,5.05,)|
Structure:
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