Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM66425
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
19400±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM66425
Synonyms:
MLS000573839 | N-methyl-4-(2-nitrovinyl)-N-phenylaniline | N-methyl-4-[(E)-2-nitroethenyl]-N-phenyl-aniline | N-methyl-4-[(E)-2-nitroethenyl]-N-phenylaniline | SMR000195428 | cid_883460 | methyl-[4-[(E)-2-nitrovinyl]phenyl]-phenyl-amine
Type:
Small organic molecule
Emp. Form.:
C15H14N2O2
Mol. Mass.:
254.2839
SMILES:
CN(c1ccccc1)c1ccc(\C=C\[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: