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Target
C-C chemokine receptor type 6
Ligand
BDBM65323
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
37700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM65323
Synonyms:
2,4-bis(chloranyl)-N-[(2-hydroxyphenyl)carbamothioyl]benzamide | 2,4-dichloro-N-[(2-hydroxyanilino)-sulfanylidenemethyl]benzamide | 2,4-dichloro-N-[(2-hydroxyphenyl)carbamothioyl]benzamide | 2,4-dichloro-N-[(2-hydroxyphenyl)thiocarbamoyl]benzamide | 2,4-dichloro-N-{[(2-hydroxyphenyl)amino]carbonothioyl}benzamide | MLS000689894 | SMR000298570 | cid_884638
Type:
Small organic molecule
Emp. Form.:
C14H10Cl2N2O2S
Mol. Mass.:
341.212
SMILES:
Oc1ccccc1NC(=S)NC(=O)c1ccc(Cl)cc1Cl
Structure:
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