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Target
C-C chemokine receptor type 6
Ligand
BDBM43883
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
23100±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM43883
Synonyms:
2-azanylidene-3-[5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-yl]-1,3-thiazolidin-4-one | 3-[5-(3-chlorobenzyl)thiazol-2-yl]-2-imino-thiazolidin-4-one | 3-[5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-yl]-2-imino-1,3-thiazolidin-4-one | 3-[5-[(3-chlorophenyl)methyl]-2-thiazolyl]-2-imino-4-thiazolidinone | MLS000707891 | SMR000288958 | cid_3157015
Type:
Small organic molecule
Emp. Form.:
C13H10ClN3OS2
Mol. Mass.:
323.821
SMILES:
Clc1cccc(Cc2cnc(s2)N2C(=N)SCC2=O)c1
Structure:
Search PDB for entries with ligand similarity: