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Target
C-C chemokine receptor type 6
Ligand
BDBM80029
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
25000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80029
Synonyms:
6-[2-(2-methoxyethylimino)-3-[1-(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)ethylamino]-1,3-thiazol-4-yl]-4H-1,4-benzoxazin-3-one | 6-[2-(2-methoxyethylimino)-3-[1-(4-oxo-1-cyclohexa-2,5-dienylidene)ethylamino]-4-thiazolyl]-4H-1,4-benzoxazin-3-one | 6-[2-(2-methoxyethylimino)-3-[1-(4-oxocyclohexa-2,5-dien-1-ylidene)ethylamino]-1,3-thiazol-4-yl]-4H-1,4-benzoxazin-3-one | 6-[3-[1-(4-ketocyclohexa-2,5-dien-1-ylidene)ethylamino]-2-(2-methoxyethylimino)-4-thiazolin-4-yl]-4H-1,4-benzoxazin-3-one | MLS000773654 | SMR000364366 | cid_6159785
Type:
Small organic molecule
Emp. Form.:
C22H22N4O4S
Mol. Mass.:
438.499
SMILES:
COCCN=c1scc(-c2ccc3OCC(=O)Nc3c2)n1N=C(C)c1ccc(O)cc1 |w:21.23,4.3|
Structure:
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