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Target
C-C chemokine receptor type 6
Ligand
BDBM80047
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
23900±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80047
Synonyms:
MLS001150495 | N-(5-isobutyl-1,3,4-thiadiazol-2-yl)-2-morpholino-5-nitro-benzamide | N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-(4-morpholinyl)-5-nitrobenzamide | N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-morpholin-4-yl-5-nitro-benzamide | N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-morpholin-4-yl-5-nitrobenzamide | SMR000706540 | cid_16959350
Type:
Small organic molecule
Emp. Form.:
C17H21N5O4S
Mol. Mass.:
391.445
SMILES:
CC(C)Cc1nnc(NC(=O)c2cc(ccc2N2CCOCC2)[N+]([O-])=O)s1
Structure:
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