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Target
C-C chemokine receptor type 6
Ligand
BDBM80059
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
30000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80059
Synonyms:
(6E)-6-[[(5-nitro-2-pyridinyl)hydrazo]methylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[[2-(5-nitropyridin-2-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[[N'-(5-nitro-2-pyridyl)hydrazino]methylene]cyclohexa-2,4-dien-1-one | MLS002608402 | SMR001527151 | cid_5355653
Type:
Small organic molecule
Emp. Form.:
C12H10N4O3
Mol. Mass.:
258.2328
SMILES:
[O-][N+](=O)c1ccc(N=[NH+]C[c-]2ccccc2=O)nc1 |w:7.6|
Structure:
Search PDB for entries with ligand similarity: