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Target
C-C chemokine receptor type 6
Ligand
BDBM80088
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
27100±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80088
Synonyms:
(5Z)-2-[(dimethylamino)methyl]-5-pentylidene-1-cyclopentanone;hydrochloride | (5Z)-2-[(dimethylamino)methyl]-5-pentylidene-cyclopentan-1-one;hydrochloride | (5Z)-2-[(dimethylamino)methyl]-5-pentylidene-cyclopentanone;hydrochloride | (5Z)-2-[(dimethylamino)methyl]-5-pentylidenecyclopentan-1-one;hydrochloride | MLS002701627 | SMR001565228 | cid_5387762
Type:
Small organic molecule
Emp. Form.:
C13H23NO
Mol. Mass.:
209.3278
SMILES:
CCCCC=C1CCC(CN(C)C)C1=O |w:4.3|
Structure:
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